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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40870 | Leukotriene E4 | LTE4 | Endogenous Metabolite |
Leukotriene E4 (LTE4) (LTE4) is produced by the action of dipeptidyl peptidase on LTD4 and is a component of the Slow Reactive Substance of Anaphylaxis (SRS-A).LTE4 is present in plasma and urine and can be used to detec... | |||
T38062 | N-acetyl Leukotriene E4 | N-acetyl Leukotriene E4 | |
N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile. This route of metabolism is prominent in the rat, but of minor importance in humans. N-acetyl LTE4 is 100 times less potent than LTC4 as a vasoconstri... | |||
T37494 | 11-trans Leukotriene E4 | 11-trans Leukotriene E4 | |
Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum. | |||
T37262 | 14,15-Leukotriene E4 | 14,15-Leukotriene E4 | |
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTE4 is a metaboli... | |||
T32680 | Leukotriene E-4 sulfone | ||
Leukotriene E-4 sulfone is a synthetic leukotriene. | |||
T23390 | SR 2640 hydrochloride | Leukotriene Receptor | |
SR 2640 hydrochloride is a competitive antagonist of leukotriene D4 and E4 and can be used in studies about leukotrienes in human asthma. | |||
T2583 | Cilastatin | MK0791 | Proteasome , Antibacterial , Antibiotic |
Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cila... | |||
T67959 | Pirodomast | Thrombin , Serine Protease | |
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas... | |||
T27904 | LY 245769 | LY-245769,LY245769 | |
LY 245769 is an inhibitor of leukotriene E4 (LTE4). | |||
T27893 | LY 203647 | LY203647,LY-203647 | |
LY 203647 is a antagonist of leukotriene D4 and E4 receptor. |